Some of it the first morning. Some of it by week three. Some of it you never feel, and it matters most. Everything here comes from a human trial at or under the dose in your mug.
Each one measured in people, at or under the amount in the mug. The marker on each card is the point on the timeline above where the trial found it.
Lower anxiety, better mood, and better sleep in healthy adults after a month21. Rhodiola and L-theanine were each studied at our dose.
Six weeks of betaine at our dose lowered homocysteine — an amino acid that tracks cardiovascular risk when high — by 12% in adults who started high23.
Women with prediabetes handled glucose better after ten weeks of NMN, at a quarter of our dose37. Twelve weeks of creatine with exercise lowered HbA1c, the three-month blood-sugar marker, in type 2 diabetes38. Both were the main thing each trial set out to measure.
Memory improved over twelve weeks of PQQ in healthy adults, at exactly our dose26, and over sixteen weeks of lion’s mane in older adults whose recall had begun to slip39. Where the decline had gone further, a year of erinacine A at half our dose improved cognition and daily function1. The deficit is what it corrects.
Twelve weeks of ubiquinol, the active form of CoQ10, at exactly our dose left adults with everyday fatigue less tired and less sleepy after a demanding mental task27.
Six to eight weeks of pterostilbene at exactly our dose lowered systolic blood pressure by 7.8 mmHg in adults with high cholesterol35.
With resistance training, creatine builds strength and lean mass in young and older adults alike — the most replicated finding in sports nutrition, across several hundred trials34. Our 5 g is the full maintenance dose, inside the range the brain studies used.
Essential Plus: everything in Essential along with extra support for immunity, joints, mood, and memory under stress.
Reishi β-glucan raised T-cell and natural-killer counts in 135 healthy adults, at exactly our dose56. In adults whose immune markers ran low, eight weeks of cordyceps raised first-line activity54.
Active adults with knee pain after exercise felt less of it by week twelve on collagen peptides, at exactly our dose58.
Reishi lifted anxiety, mood, and vitality scores in healthy young women over a month59.